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Association details:
| Biomarker: | EGFR G2607A |
|---|---|
| Cancer: | Lung Cancer |
| Drug: | Gilotrif (afatinib) (pan-HER inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Afatinib in the treatment of brain metastases of lung cancer with one rare EGFR mutation
Published date:
07/12/2021
Excerpt:
...a rare mutation of EGFR G2607A (rs1050171) in two patients over 50 years of age with brain metastasis of lung cancer....study provides a support that afatinib may be a reasonable therapeutic option for patients with brain metastasis of lung cancer.
DOI:
10.1097/CAD.0000000000001138