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Association details:
Biomarker:
MSI-H/dMMR
Cancer:
Colon Cancer
Drug:
Jemperli (dostarlimab-gxly)
(
PD1 inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
NCCN
Excerpt:
Colon Cancer...SYSTEMIC THERAPY FOR ADVANCED OR METASTATIC DISEASE - CHEMOTHERAPY REGIMENS...Dostarlimab-gxly39 (dMMR/MSI-H only)
Evidence Level:
Sensitive: C2 – Inclusion Criteria
New
Source:
clinicaltrials.gov
Title:
Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer
Excerpt:
...- Has a tumor demonstrating the presence of either dMMR status or MSI-H...
Trial ID:
AZUR-2
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