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Association details:
| Biomarker: | TTN 10361-5delT |
|---|---|
| Cancer: | Chronic Myeloid Leukemia |
| Drug: | imatinib (Bcr-abl inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
IDENTIFICATION OF GENOMIC VARIANTS ASSOCIATED WITH LONG TERM MOLECULAR RESPONSE TO TYROSINE KINASE INHIBITORS IN CHRONIC MYELOID LEUKEMIA
Published date:
05/14/2020
Excerpt:
Novel genes/variants associated exclusively with long-term CML responders to imatinib and absent in all control groups, namely PTPN22, TTN, PDLIM4, CACNA1B, CELF2, ANO5, MYO16, TP53, KCNJ12 and RAI1 genes...