[{"id":"e719e53a-348e-4f61-a2ec-8427efdc6994","acronym":"","url":"https://clinicaltrials.gov/study/NCT05846867","created_at":"2023-05-06T14:04:17.161Z","updated_at":"2024-07-02T16:35:48.741Z","phase":"Phase 1/2","brief_title":"Study of AK119 and AK 112 With or Without Chemotherapy for Colorectal Cancer Patients","source_id_and_acronym":"NCT05846867","lead_sponsor":"Akeso","biomarkers":" MLH1 • MSH6 • MSH2","pipe":" | ","alterations":" PD-L1 expression • MSH6 expression","tags":["MLH1 • MSH6 • MSH2"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e PD-L1 expression • MSH6 expression"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e 5-fluorouracil • oxaliplatin • irinotecan • leucovorin calcium • Yidafan (ivonescimab) • drebuxelimab (AK119)"],"overall_status":"Not yet recruiting","enrollment":" Enrollment 72","initiation":"Initiation: 05/10/2023","start_date":" 05/10/2023","primary_txt":" Primary completion: 05/10/2024","primary_completion_date":" 05/10/2024","study_txt":" Completion: 07/10/2025","study_completion_date":" 07/10/2025","last_update_posted":"2023-05-08"}]