[{"id":"748ec904-db93-4ec4-8834-8cbd50058a45","acronym":"","url":"https://clinicaltrials.gov/study/NCT02864381","created_at":"2021-01-18T14:03:42.810Z","updated_at":"2024-07-02T16:36:40.902Z","phase":"Phase 2","brief_title":"Study to Evaluate the Efficacy and Safety of Andecaliximab Combined With Nivolumab Versus Nivolumab Alone in Adults With Unresectable or Recurrent Gastric or Gastroesophageal Junction Adenocarcinoma","source_id_and_acronym":"NCT02864381","lead_sponsor":"Gilead Sciences","biomarkers":" PD-L1","pipe":"","alterations":" ","tags":["PD-L1"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e Opdivo (nivolumab) • andecaliximab (GS-5745)"],"overall_status":"Completed","enrollment":" Enrollment 144","initiation":"Initiation: 09/01/2016","start_date":" 09/01/2016","primary_txt":" Primary completion: 11/08/2017","primary_completion_date":" 11/08/2017","study_txt":" Completion: 08/23/2019","study_completion_date":" 08/23/2019","last_update_posted":"2020-09-18"},{"id":"11f2b7a9-d56e-449d-b5fb-ad3668a3f5c5","acronym":"","url":"https://clinicaltrials.gov/study/NCT01803282","created_at":"2021-01-18T07:59:16.880Z","updated_at":"2024-07-02T16:36:44.574Z","phase":"Phase 1","brief_title":"Study to Evaluate the Safety and Tolerability of Andecaliximab as Monotherapy and in Combination With Chemotherapy in Participants With Advanced Solid Tumors","source_id_and_acronym":"NCT01803282","lead_sponsor":"Gilead Sciences","biomarkers":" HER-2 • ALK • EML4","pipe":" | ","alterations":" EGFR mutation • HER-2 negative • EML4-ALK fusion • ALK fusion • ALK translocation","tags":["HER-2 • ALK • EML4"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e EGFR mutation • HER-2 negative • EML4-ALK fusion • ALK fusion • ALK translocation"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e Avastin (bevacizumab) • carboplatin • gemcitabine • 5-fluorouracil • albumin-bound paclitaxel • pemetrexed • oxaliplatin • irinotecan • leucovorin calcium • andecaliximab (GS-5745)"],"overall_status":"Completed","enrollment":" Enrollment 236","initiation":"Initiation: 03/29/2013","start_date":" 03/29/2013","primary_txt":" Primary completion: 04/23/2019","primary_completion_date":" 04/23/2019","study_txt":" Completion: 04/23/2019","study_completion_date":" 04/23/2019","last_update_posted":"2020-06-02"}]