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CHRISTELLE","lead_sponsor":"AstraZeneca","biomarkers":" BRCA1 • BRCA2","pipe":" | ","alterations":" BRCA2 mutation • BRCA1 mutation • BRCA1 mutation + BRCA2 mutation","tags":["BRCA1 • BRCA2"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e BRCA2 mutation • BRCA1 mutation • BRCA1 mutation + BRCA2 mutation"],"overall_status":"Completed","enrollment":" Enrollment 207","initiation":"Initiation: 03/19/2020","start_date":" 03/19/2020","primary_txt":" Primary completion: 11/13/2020","primary_completion_date":" 11/13/2020","study_txt":" Completion: 11/13/2020","study_completion_date":" 11/13/2020","last_update_posted":"2021-10-26"},{"id":"cbf09b9b-a2c0-4dc6-a145-f3dcbb85965c","acronym":"","url":"https://clinicaltrials.gov/study/NCT01623349","created_at":"2021-01-18T06:57:53.787Z","updated_at":"2025-02-25T15:05:16.877Z","phase":"Phase 1","brief_title":"Phase I Study of the Oral PI3kinase Inhibitor BKM120 or BYL719 and the Oral PARP Inhibitor Olaparib in Patients With Recurrent Triple Negative Breast Cancer or High Grade Serous Ovarian Cancer","source_id_and_acronym":"NCT01623349","lead_sponsor":"Dana-Farber Cancer Institute","biomarkers":" BRCA1 • BRCA","pipe":" | ","alterations":" BRCA2 mutation • BRCA1 mutation • BRCA1 mutation + BRCA2 mutation","tags":["BRCA1 • BRCA"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e BRCA2 mutation • BRCA1 mutation • BRCA1 mutation + BRCA2 mutation"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e Lynparza (olaparib) • Piqray (alpelisib) • buparlisib (AN2025)"],"overall_status":"Completed","enrollment":" Enrollment 118","initiation":"Initiation: 09/01/2012","start_date":" 09/01/2012","primary_txt":" Primary completion: 05/01/2019","primary_completion_date":" 05/01/2019","study_txt":" Completion: 12/01/2020","study_completion_date":" 12/01/2020","last_update_posted":"2021-02-10"},{"id":"6038dbc0-ffd8-4c83-8918-bd2e2c956181","acronym":"PREDICT","url":"https://clinicaltrials.gov/study/NCT03082976","created_at":"2021-01-18T15:11:15.812Z","updated_at":"2024-07-02T16:36:43.129Z","phase":"","brief_title":"Prevalence of BRCA1 and BRCA2 Mutations in Ovarian Cancer Patients in the Gulf Region","source_id_and_acronym":"NCT03082976 - PREDICT","lead_sponsor":"AstraZeneca","biomarkers":" BRCA1 • BRCA2 • BRCA","pipe":" | ","alterations":" BRCA2 mutation • BRCA1 mutation • BRCA1 mutation + BRCA2 mutation • BRCA mutation","tags":["BRCA1 • BRCA2 • BRCA"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e BRCA2 mutation • BRCA1 mutation • BRCA1 mutation + BRCA2 mutation • BRCA mutation"],"overall_status":"Completed","enrollment":" Enrollment 108","initiation":"Initiation: 07/16/2017","start_date":" 07/16/2017","primary_txt":" Primary completion: 07/24/2019","primary_completion_date":" 07/24/2019","study_txt":" Completion: 07/24/2019","study_completion_date":" 07/24/2019","last_update_posted":"2020-07-16"},{"id":"b753693a-72f0-4da7-be1b-b299d0ad8956","acronym":"FLABRA","url":"https://clinicaltrials.gov/study/NCT02984423","created_at":"2021-01-18T14:41:20.658Z","updated_at":"2024-07-02T16:36:43.377Z","phase":"","brief_title":"FLABRA: Frontline Approach for BRCA Testing in OC Treatment naïve Population. A LATIN AMERICA Epidemiologic Study","source_id_and_acronym":"NCT02984423 - FLABRA","lead_sponsor":"AstraZeneca","biomarkers":" BRCA1 • BRCA2 • BRCA","pipe":" | ","alterations":" BRCA2 mutation • BRCA1 mutation + BRCA2 mutation • BRCA mutation","tags":["BRCA1 • BRCA2 • BRCA"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e BRCA2 mutation • BRCA1 mutation + BRCA2 mutation • BRCA mutation"],"overall_status":"Completed","enrollment":" Enrollment 471","initiation":"Initiation: 12/27/2016","start_date":" 12/27/2016","primary_txt":" Primary completion: 06/30/2019","primary_completion_date":" 06/30/2019","study_txt":" Completion: 06/30/2019","study_completion_date":" 06/30/2019","last_update_posted":"2020-07-10"},{"id":"59c77bee-74da-4081-96e3-d3c6eaa72a3b","acronym":"","url":"https://clinicaltrials.gov/study/NCT02514499","created_at":"2021-01-18T12:09:00.478Z","updated_at":"2024-07-02T16:36:57.766Z","phase":"","brief_title":"Multiplex Testing for Evaluation of Breast Cancer Risk, Longitudinal Study","source_id_and_acronym":"NCT02514499","lead_sponsor":"Abramson Cancer Center of the University of Pennsylvania","biomarkers":" BRCA1 • BRCA2","pipe":" | ","alterations":" BRCA2 mutation • BRCA1 mutation • BRCA1 mutation + BRCA2 mutation • BRCA1 negative","tags":["BRCA1 • BRCA2"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e BRCA2 mutation • BRCA1 mutation • BRCA1 mutation + BRCA2 mutation • BRCA1 negative"],"overall_status":"Completed","enrollment":" Enrollment 350","initiation":"Initiation: 07/01/2014","start_date":" 07/01/2014","primary_txt":" Primary completion: 10/01/2018","primary_completion_date":" 10/01/2018","study_txt":" Completion: 10/01/2018","study_completion_date":" 10/01/2018","last_update_posted":"2019-07-24"},{"id":"3d44efbf-1548-46dd-ae4f-9be7440f6e5a","acronym":"","url":"https://clinicaltrials.gov/study/NCT00588263","created_at":"2021-01-18T02:10:16.832Z","updated_at":"2024-07-02T16:37:13.816Z","phase":"","brief_title":"Anonymous Testing of Pathology Specimens for BRCA Mutations in Ashkenazi Jewish Individuals Who Have Cancer","source_id_and_acronym":"NCT00588263","lead_sponsor":"Memorial Sloan Kettering Cancer Center","biomarkers":" BRCA1 • BRCA2 • BRCA","pipe":" | ","alterations":" BRCA2 mutation • BRCA1 mutation • BRCA1 mutation + BRCA2 mutation","tags":["BRCA1 • BRCA2 • BRCA"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e BRCA2 mutation • BRCA1 mutation • BRCA1 mutation + BRCA2 mutation"],"overall_status":"Withdrawn","enrollment":"","initiation":"Initiation: 07/01/2000","start_date":" 07/01/2000","primary_txt":" Primary completion: 07/01/2018","primary_completion_date":" 07/01/2018","study_txt":" Completion: 07/01/2018","study_completion_date":" 07/01/2018","last_update_posted":"2018-02-19"}]