[{"id":"47d84427-9b27-4617-9de8-ee61b983e20c","acronym":"","url":"https://clinicaltrials.gov/study/NCT04499118","created_at":"2021-01-18T21:33:14.763Z","updated_at":"2024-07-02T16:36:42.304Z","phase":"Phase 2","brief_title":"AT Versus TP as Neoadjuvant Chemotherapy in Patients With HER2-negative Early Breast Cancer","source_id_and_acronym":"NCT04499118","lead_sponsor":"Sichuan Provincial People's Hospital","biomarkers":" HER-2 • PGR • BRCA","pipe":" | ","alterations":" HER-2 positive • HER-2 negative • ER positive + PGR positive • PGR positive • BRCA mutation • High HRD score","tags":["HER-2 • PGR • BRCA"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e HER-2 positive • HER-2 negative • ER positive + PGR positive • PGR positive • BRCA mutation • High HRD score"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e cisplatin • carboplatin • paclitaxel • docetaxel • albumin-bound paclitaxel • epirubicin"],"overall_status":"Not yet recruiting","enrollment":" Enrollment 100","initiation":"Initiation: 08/01/2020","start_date":" 08/01/2020","primary_txt":" Primary completion: 08/01/2021","primary_completion_date":" 08/01/2021","study_txt":" Completion: 08/01/2021","study_completion_date":" 08/01/2021","last_update_posted":"2020-08-05"},{"id":"89075d7f-c908-44df-b248-9e0bc64aaac5","acronym":"","url":"https://clinicaltrials.gov/study/NCT03032614","created_at":"2021-01-18T14:55:37.431Z","updated_at":"2024-07-02T16:37:17.214Z","phase":"Phase 2","brief_title":"Combination of Carboplatin, Eribulin and Veliparib in Stage IV Cancer Patients","source_id_and_acronym":"NCT03032614","lead_sponsor":"The University of Texas Health Science Center at San Antonio","biomarkers":" BRCA1 • BRCA2 • PTEN","pipe":" | ","alterations":" PTEN deletion • High HRD score","tags":["BRCA1 • BRCA2 • PTEN"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e PTEN deletion • High HRD score"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e cisplatin • carboplatin • Halaven (eribulin mesylate) • veliparib (ABT-888)"],"overall_status":"Withdrawn","enrollment":"","initiation":"Initiation: 09/30/2017","start_date":" 09/30/2017","primary_txt":" Primary completion: 03/31/2019","primary_completion_date":" 03/31/2019","study_txt":" Completion: 04/30/2020","study_completion_date":" 04/30/2020","last_update_posted":"2017-10-10"}]