[{"id":"2c6b4f69-4124-49bc-8cc4-6915ea81dc11","acronym":"INDUCE-1","url":"https://clinicaltrials.gov/study/NCT02723955","created_at":"2021-01-17T17:58:41.023Z","updated_at":"2025-02-25T16:04:31.793Z","phase":"Phase 1","brief_title":"Dose Escalation and Expansion Study of GSK3359609 in Participants With Selected Advanced Solid Tumors (INDUCE-1)","source_id_and_acronym":"NCT02723955 - INDUCE-1","lead_sponsor":"GlaxoSmithKline","biomarkers":" MSI • ICOS","pipe":" | ","alterations":" MSI-H/dMMR","tags":["MSI • ICOS"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e MSI-H/dMMR"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e Keytruda (pembrolizumab) • cisplatin • carboplatin • gemcitabine • paclitaxel • docetaxel • 5-fluorouracil • pemetrexed • Jemperli (dostarlimab-gxly) • bintrafusp alfa (M7824) • cobolimab (TSR-022) • feladilimab (GSK3359609) • GSK3174998"],"overall_status":"Completed","enrollment":" Enrollment 829","initiation":"Initiation: 06/23/2016","start_date":" 06/23/2016","primary_txt":" Primary completion: 07/05/2023","primary_completion_date":" 07/05/2023","study_txt":" Completion: 07/05/2023","study_completion_date":" 07/05/2023","last_update_posted":"2024-12-27"},{"id":"3503eb0c-ef4c-41cc-9d2c-ae9798e2ea91","acronym":"","url":"https://clinicaltrials.gov/study/NCT05553808","created_at":"2022-09-23T17:07:19.793Z","updated_at":"2024-07-02T16:35:57.411Z","phase":"Phase 2","brief_title":"Platform Trial of Novel Regimens Versus Standard of Care (SoC) in Participants With Non-small Cell Lung Cancer (NSCLC) - Sub-study 1","source_id_and_acronym":"NCT05553808","lead_sponsor":"GlaxoSmithKline","biomarkers":" BRAF","pipe":"","alterations":" ","tags":["BRAF"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e docetaxel • feladilimab (GSK3359609)"],"overall_status":"Completed","enrollment":" Enrollment 105","initiation":"Initiation: 01/24/2019","start_date":" 01/24/2019","primary_txt":" Primary completion: 09/23/2021","primary_completion_date":" 09/23/2021","study_txt":" Completion: 09/23/2021","study_completion_date":" 09/23/2021","last_update_posted":"2023-01-19"}]