[{"id":"cb2c4839-09e4-41a3-9033-1bd13594665c","acronym":"","url":"https://clinicaltrials.gov/study/NCT01860937","created_at":"2021-01-18T08:19:12.565Z","updated_at":"2024-07-02T16:34:38.169Z","phase":"Phase 1","brief_title":"T-Lymphocytes Genetically Targeted to the B-Cell Specific Antigen CD19 in Pediatric and Young Adult Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia","source_id_and_acronym":"NCT01860937","lead_sponsor":"Memorial Sloan Kettering Cancer Center","biomarkers":" KMT2A • IKZF1","pipe":" | ","alterations":" MLL rearrangement • IKZF1 deletion","tags":["KMT2A • IKZF1"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e MLL rearrangement • IKZF1 deletion"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e cyclophosphamide • vadacabtagene leraleucel (JCAR015)"],"overall_status":"Active, not recruiting","enrollment":" Enrollment 23","initiation":"Initiation: 05/01/2013","start_date":" 05/01/2013","primary_txt":" Primary completion: 05/01/2025","primary_completion_date":" 05/01/2025","study_txt":" Completion: 05/01/2025","study_completion_date":" 05/01/2025","last_update_posted":"2024-06-05"},{"id":"edc31125-8b7c-4865-bea9-08a628819ebd","acronym":"","url":"https://clinicaltrials.gov/study/NCT03889951","created_at":"2021-01-18T19:10:07.608Z","updated_at":"2024-07-02T16:37:01.296Z","phase":"","brief_title":"Detection of IKZF1 Deletion Mutation in Patients With Acute Lymphoblastic Leukemia and Its Impact in Therapy","source_id_and_acronym":"NCT03889951","lead_sponsor":"Assiut University","biomarkers":" ABL1 • BCR • IKZF1","pipe":" | ","alterations":" IKZF1 deletion • IKZF1 mutation","tags":["ABL1 • BCR • IKZF1"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e IKZF1 deletion • IKZF1 mutation"],"overall_status":"Unknown status","enrollment":" Enrollment 50","initiation":"Initiation: 04/01/2019","start_date":" 04/01/2019","primary_txt":" Primary completion: 04/01/2020","primary_completion_date":" 04/01/2020","study_txt":" Completion: 05/01/2020","study_completion_date":" 05/01/2020","last_update_posted":"2019-03-26"}]