[{"id":"4199cb8a-376d-4913-97ce-8246b0269e5a","acronym":"","url":"https://clinicaltrials.gov/study/NCT01702714","created_at":"2021-01-18T07:24:24.428Z","updated_at":"2024-07-02T16:37:27.751Z","phase":"Phase 1","brief_title":"A Study of RO5083945 in Combination With Cisplatin and Gemcitabine or Carboplatin and Paclitaxel in Patients With Advanced or Recurrent Non-Small Cell Lung Cancer of Squamous Histology Who Have Not Received Prior Chemotherapy for The Metastatic Disease","source_id_and_acronym":"NCT01702714","lead_sponsor":"Hoffmann-La Roche","biomarkers":" EGFR","pipe":"","alterations":" ","tags":["EGFR"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e cisplatin • carboplatin • gemcitabine • paclitaxel • imgatuzumab (RO5083945)"],"overall_status":"Withdrawn","enrollment":"","initiation":"Initiation: 07/01/2014","start_date":" 07/01/2014","primary_txt":" Primary completion: 02/01/2016","primary_completion_date":" 02/01/2016","study_txt":" Completion: 02/01/2016","study_completion_date":" 02/01/2016","last_update_posted":"2016-11-04"},{"id":"80554a9c-5bce-4fc0-aa1b-e4457b9ec81f","acronym":"","url":"https://clinicaltrials.gov/study/NCT00721266","created_at":"2021-01-18T02:42:24.919Z","updated_at":"2024-07-02T16:37:27.862Z","phase":"Phase 1","brief_title":"A Dose-Escalation Study of RO5083945 in Patients With Metastatic and/or Locally Advanced Malignant Epidermal Growth Factor Receptor (EGFR)+ Solid Tumors.","source_id_and_acronym":"NCT00721266","lead_sponsor":"Hoffmann-La Roche","biomarkers":" EGFR • KRAS","pipe":" | ","alterations":" KRAS mutation • EGFR mutation • EGFR expression","tags":["EGFR • KRAS"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e KRAS mutation • EGFR mutation • EGFR expression"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e imgatuzumab (RO5083945)"],"overall_status":"Completed","enrollment":" Enrollment 102","initiation":"Initiation: 06/01/2008","start_date":" 06/01/2008","primary_txt":" Primary completion: 06/01/2011","primary_completion_date":" 06/01/2011","study_txt":" Completion: 06/01/2011","study_completion_date":" 06/01/2011","last_update_posted":"2016-11-02"}]