[{"id":"154afa1b-c0be-412f-b05f-4aaae6570e78","acronym":"","url":"https://clinicaltrials.gov/study/NCT04015700","created_at":"2021-01-18T19:43:25.060Z","updated_at":"2024-07-02T16:35:15.562Z","phase":"Phase 1","brief_title":"Neoantigen-based Personalized DNA Vaccine in Patients With Newly Diagnosed, Unmethylated Glioblastoma","source_id_and_acronym":"NCT04015700","lead_sponsor":"Washington University School of Medicine","biomarkers":" IDH1 • IDH2 • MGMT","pipe":" | ","alterations":" IDH2 mutation","tags":["IDH1 • IDH2 • MGMT"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e IDH2 mutation"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e rocakinogene sifuplasmid (INO-9012) • GNOS-PV01 • neoantigen DNA vaccine"],"overall_status":"Active, not recruiting","enrollment":" Enrollment 9","initiation":"Initiation: 07/14/2020","start_date":" 07/14/2020","primary_txt":" Primary completion: 05/13/2022","primary_completion_date":" 05/13/2022","study_txt":" Completion: 12/31/2024","study_completion_date":" 12/31/2024","last_update_posted":"2024-03-08"},{"id":"24b439dc-7d7b-496b-a965-b7e47c369dd2","acronym":"","url":"https://clinicaltrials.gov/study/NCT05743595","created_at":"2023-02-24T16:01:26.750Z","updated_at":"2024-07-02T16:35:16.529Z","phase":"Phase 1","brief_title":"Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma","source_id_and_acronym":"NCT05743595","lead_sponsor":"Washington University School of Medicine","biomarkers":" IDH1 • IDH2 • MGMT","pipe":" | ","alterations":" IDH2 mutation • MGMT promoter methylation • IDH wild-type","tags":["IDH1 • IDH2 • MGMT"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e IDH2 mutation • MGMT promoter methylation • IDH wild-type"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e Zynyz (retifanlimab-dlwr) • neoantigen DNA vaccine"],"overall_status":"Recruiting","enrollment":" Enrollment 12","initiation":"Initiation: 10/27/2023","start_date":" 10/27/2023","primary_txt":" Primary completion: 01/31/2025","primary_completion_date":" 01/31/2025","study_txt":" Completion: 10/31/2027","study_completion_date":" 10/31/2027","last_update_posted":"2024-03-04"}]