[{"id":"c888c59b-5866-45b5-b5e1-8236364f4e96","acronym":"ATTAIN","url":"https://clinicaltrials.gov/study/NCT02915744","created_at":"2021-01-18T14:18:52.943Z","updated_at":"2024-07-02T16:35:50.577Z","phase":"Phase 3","brief_title":"A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine","source_id_and_acronym":"NCT02915744 - ATTAIN","lead_sponsor":"Nektar Therapeutics","biomarkers":" HER-2","pipe":"","alterations":" ","tags":["HER-2"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e gemcitabine • docetaxel • capecitabine • albumin-bound paclitaxel • irinotecan • Halaven (eribulin mesylate) • vinorelbine tartrate • Ixempra (ixabepilone) • Onzeald (etirinotecan pegol)"],"overall_status":"Completed","enrollment":" Enrollment 178","initiation":"Initiation: 11/01/2016","start_date":" 11/01/2016","primary_txt":" Primary completion: 07/01/2020","primary_completion_date":" 07/01/2020","study_txt":" Completion: 07/01/2020","study_completion_date":" 07/01/2020","last_update_posted":"2023-04-14"},{"id":"259726d8-079d-4972-9aa9-ab1e1c2f8760","acronym":"","url":"https://clinicaltrials.gov/study/NCT00856375","created_at":"2021-01-18T03:15:47.287Z","updated_at":"2024-07-02T16:36:28.064Z","phase":"Phase 2","brief_title":"NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer","source_id_and_acronym":"NCT00856375","lead_sponsor":"Nektar Therapeutics","biomarkers":" KRAS • RAS","pipe":" | ","alterations":" KRAS mutation • RAS mutation","tags":["KRAS • RAS"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e KRAS mutation • RAS mutation"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e irinotecan • Onzeald (etirinotecan pegol)"],"overall_status":"Completed","enrollment":" Enrollment 83","initiation":"Initiation: 12/01/2008","start_date":" 12/01/2008","primary_txt":" Primary completion: 07/01/2014","primary_completion_date":" 07/01/2014","study_txt":" Completion: 12/01/2014","study_completion_date":" 12/01/2014","last_update_posted":"2021-07-12"}]