[{"id":"555f4a0d-f843-45d3-937e-da35717f6f0f","acronym":"","url":"https://clinicaltrials.gov/study/NCT03893955","created_at":"2021-01-18T19:10:50.774Z","updated_at":"2024-07-02T16:34:37.718Z","phase":"Phase 1","brief_title":"A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-927 With ABBV-368, Budigalimab (ABBV-181) and/or Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors","source_id_and_acronym":"NCT03893955","lead_sponsor":"AbbVie","biomarkers":" HER-2 • ER • PGR","pipe":" | ","alterations":" HER-2 negative • PD-L1 negative","tags":["HER-2 • ER • PGR"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e HER-2 negative • PD-L1 negative"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e carboplatin • albumin-bound paclitaxel • budigalimab (ABBV-181) • giloralimab (ABBV-927) • revdofilimab (ABBV-368)"],"overall_status":"Active, not recruiting","enrollment":" Enrollment 150","initiation":"Initiation: 05/21/2019","start_date":" 05/21/2019","primary_txt":" Primary completion: 09/29/2024","primary_completion_date":" 09/29/2024","study_txt":" Completion: 09/29/2024","study_completion_date":" 09/29/2024","last_update_posted":"2024-06-06"},{"id":"dad65528-e8ce-42f1-a557-69b26a4858c6","acronym":"","url":"https://clinicaltrials.gov/study/NCT03071757","created_at":"2021-01-18T15:07:57.819Z","updated_at":"2024-07-02T16:36:11.278Z","phase":"Phase 1","brief_title":"A Study of the Safety, Tolerability and Pharmacokinetics of ABBV-368 as a Single Agent and Combination in Subjects With Locally Advanced or Metastatic Solid Tumors","source_id_and_acronym":"NCT03071757","lead_sponsor":"AbbVie","biomarkers":" PD-L1","pipe":"","alterations":" ","tags":["PD-L1"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e budigalimab (ABBV-181) • revdofilimab (ABBV-368)"],"overall_status":"Completed","enrollment":" Enrollment 139","initiation":"Initiation: 03/21/2017","start_date":" 03/21/2017","primary_txt":" Primary completion: 04/13/2022","primary_completion_date":" 04/13/2022","study_txt":" Completion: 04/13/2022","study_completion_date":" 04/13/2022","last_update_posted":"2022-04-28"}]