[{"id":"95c5fde2-39ca-4ca7-bf06-565bdb7900a5","acronym":"","url":"https://clinicaltrials.gov/study/NCT05429697","created_at":"2022-06-23T16:00:09.688Z","updated_at":"2024-07-02T16:36:03.439Z","phase":"Phase 2b","brief_title":"Study of SMT-NK Inj. Plus Pembrolizumab vs Pembrolizumab Monotherapy in Patients With Advanced Biliary Tract Cancer","source_id_and_acronym":"NCT05429697","lead_sponsor":"SMT bio Co., Ltd.","biomarkers":" PD-L1 • MSI • MLH1 • MSH6 • MSH2","pipe":" | ","alterations":" PD-L1 expression • MSI-H/dMMR","tags":["PD-L1 • MSI • MLH1 • MSH6 • MSH2"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e PD-L1 expression • MSI-H/dMMR"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e Keytruda (pembrolizumab) • SMT-NK"],"overall_status":"Recruiting","enrollment":" Enrollment 128","initiation":"Initiation: 06/09/2022","start_date":" 06/09/2022","primary_txt":" Primary completion: 01/08/2025","primary_completion_date":" 01/08/2025","study_txt":" Completion: 06/08/2026","study_completion_date":" 06/08/2026","last_update_posted":"2022-09-27"},{"id":"d93f7d91-01cb-458b-9b00-ae07bb130d19","acronym":"","url":"https://clinicaltrials.gov/study/NCT03937895","created_at":"2021-01-18T19:23:34.810Z","updated_at":"2024-07-02T16:36:14.526Z","phase":"Phase 1/2","brief_title":"Allogeneic NK Cell (\"SMT-NK\") in Combination With Pembrolizumab in Advanced Biliary Tract Cancer","source_id_and_acronym":"NCT03937895","lead_sponsor":"SMT bio Co., Ltd.","biomarkers":" PD-L1 • MSI • MLH1 • MSH6 • MSH2","pipe":" | ","alterations":" PD-L1 expression • MSI-H/dMMR","tags":["PD-L1 • MSI • MLH1 • MSH6 • MSH2"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e PD-L1 expression • MSI-H/dMMR"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e Keytruda (pembrolizumab) • gemcitabine • SMT-NK"],"overall_status":"Completed","enrollment":" Enrollment 40","initiation":"Initiation: 12/03/2019","start_date":" 12/03/2019","primary_txt":" Primary completion: 06/08/2021","primary_completion_date":" 06/08/2021","study_txt":" Completion: 06/08/2021","study_completion_date":" 06/08/2021","last_update_posted":"2022-03-29"}]