[{"id":"6785cd81-0dc9-489d-83a3-ebe2f7ac3a5d","acronym":"","url":"https://clinicaltrials.gov/study/NCT05767892","created_at":"2023-03-14T14:01:43.213Z","updated_at":"2024-07-02T16:35:51.445Z","phase":"Phase 3","brief_title":"YK-029A as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutations","source_id_and_acronym":"NCT05767892","lead_sponsor":"Suzhou Puhe Pharmaceutical Technology Co., LTD","biomarkers":" HER-2","pipe":" | ","alterations":" EGFR L858R • EGFR exon 19 deletion • EGFR T790M • EGFR exon 20 insertion • EGFR L861Q • EGFR G719X • EGFR S768I • EGFR exon 20 mutation","tags":["HER-2"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e EGFR L858R • EGFR exon 19 deletion • EGFR T790M • EGFR exon 20 insertion • EGFR L861Q • EGFR G719X • EGFR S768I • EGFR exon 20 mutation"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e cisplatin • carboplatin • pemetrexed • PH001"],"overall_status":"Not yet recruiting","enrollment":" Enrollment 350","initiation":"Initiation: 05/01/2023","start_date":" 05/01/2023","primary_txt":" Primary completion: 07/30/2025","primary_completion_date":" 07/30/2025","study_txt":" Completion: 12/31/2026","study_completion_date":" 12/31/2026","last_update_posted":"2023-04-05"},{"id":"32963fcb-fb18-4a7a-9153-fc3a5a7b7637","acronym":"","url":"https://clinicaltrials.gov/study/NCT05767866","created_at":"2023-03-14T14:01:42.806Z","updated_at":"2024-07-02T16:35:53.096Z","phase":"Phase 1/2","brief_title":"Assessing an Oral EGFR Inhibitor,YK-209A in Patients Who Have Advanced Non-small Cell Lung Cancer With EGFR","source_id_and_acronym":"NCT05767866","lead_sponsor":"Suzhou Puhe Pharmaceutical Technology Co., LTD","biomarkers":" EGFR","pipe":" | ","alterations":" EGFR mutation • EGFR T790M • EGFR L861Q • EGFR G719X • EGFR S768I","tags":["EGFR"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e EGFR mutation • EGFR T790M • EGFR L861Q • EGFR G719X • EGFR S768I"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e PH001"],"overall_status":"Recruiting","enrollment":" Enrollment 160","initiation":"Initiation: 03/30/2018","start_date":" 03/30/2018","primary_txt":" Primary completion: 12/30/2023","primary_completion_date":" 12/30/2023","study_txt":" Completion: 05/30/2024","study_completion_date":" 05/30/2024","last_update_posted":"2023-03-17"}]