[{"id":"39082f6c-8d92-4c46-9e0c-a8aeaf83e623","acronym":"","url":"https://clinicaltrials.gov/study/NCT05173805","created_at":"2021-12-30T14:55:47.563Z","updated_at":"2024-07-02T16:35:42.768Z","phase":"Phase 1/2","brief_title":"Phase I Clinical Study of YL-15293 in Patients With Advanced Solid Tumor With KRAS Mutation","source_id_and_acronym":"NCT05173805","lead_sponsor":"Shanghai YingLi Pharmaceutical Co. Ltd.","biomarkers":" PD-L1 • KRAS • MSI • PD-1","pipe":" | ","alterations":" KRAS mutation • MSI-H/dMMR • KRAS G12C • KRAS G12D • KRAS G12V • KRAS G12A • KRAS G12","tags":["PD-L1 • KRAS • MSI • PD-1"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e KRAS mutation • MSI-H/dMMR • KRAS G12C • KRAS G12D • KRAS G12V • KRAS G12A • KRAS G12"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e YL-15293"],"overall_status":"Enrolling by invitation","enrollment":" Enrollment 150","initiation":"Initiation: 01/30/2022","start_date":" 01/30/2022","primary_txt":" Primary completion: 04/30/2024","primary_completion_date":" 04/30/2024","study_txt":" Completion: 12/30/2024","study_completion_date":" 12/30/2024","last_update_posted":"2023-07-18"},{"id":"60ff5968-1f14-4145-b080-97aeaa138217","acronym":"","url":"https://clinicaltrials.gov/study/NCT05119933","created_at":"2021-11-15T12:53:32.653Z","updated_at":"2024-07-02T16:36:20.735Z","phase":"Phase 1/2","brief_title":"A Phase 1/2, Study of YL-15293 in Subjects With Advanced Solid Tumors With a KRAS G12C Mutation","source_id_and_acronym":"NCT05119933","lead_sponsor":"Shanghai YingLi Pharmaceutical Co. Ltd.","biomarkers":" KRAS","pipe":" | ","alterations":" KRAS G12C • KRAS G12","tags":["KRAS"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e KRAS G12C • KRAS G12"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e YL-15293"],"overall_status":"Recruiting","enrollment":" Enrollment 55","initiation":"Initiation: 11/09/2021","start_date":" 11/09/2021","primary_txt":" Primary completion: 06/01/2023","primary_completion_date":" 06/01/2023","study_txt":" Completion: 12/01/2023","study_completion_date":" 12/01/2023","last_update_posted":"2021-11-15"}]