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DRUG:

Haizexin (risovalisib)

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Company:

HaiHe Biopharma, Otsuka

Drug class:

PI3Kα inhibitor

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PIK3CA mutation	Ovarian Cancer	PIK3CA mutation	Ovarian Cancer	risovalisib Sensitive: C2 – Inclusion Criteria risovalisib Sensitive : C2	risovalisib Sensitive: C2 – Inclusion Criteria risovalisib Sensitive : C2
PIK3CA mutation	Breast Cancer	PIK3CA mutation	Breast Cancer	risovalisib Sensitive: C2 – Inclusion Criteria risovalisib Sensitive : C2	risovalisib Sensitive: C2 – Inclusion Criteria risovalisib Sensitive : C2
PIK3CA E545K	Gastric Cancer	PIK3CA E545K	Gastric Cancer	risovalisib Sensitive: C4 – Case Studies risovalisib Sensitive : C4	risovalisib Sensitive: C4 – Case Studies risovalisib Sensitive : C4
PIK3CA E545K	Breast Cancer	PIK3CA E545K	Breast Cancer	risovalisib Sensitive: C4 – Case Studies risovalisib Sensitive : C4	risovalisib Sensitive: C4 – Case Studies risovalisib Sensitive : C4
PIK3CA E545K	Ovarian Cancer	PIK3CA E545K	Ovarian Cancer	risovalisib Sensitive: C4 – Case Studies risovalisib Sensitive : C4	risovalisib Sensitive: C4 – Case Studies risovalisib Sensitive : C4
PIK3CA E545A	Ovarian Cancer	PIK3CA E545A	Ovarian Cancer	risovalisib Sensitive: C4 – Case Studies risovalisib Sensitive : C4	risovalisib Sensitive: C4 – Case Studies risovalisib Sensitive : C4
PIK3CA E545K	HER2 Negative Breast Cancer	PIK3CA E545K	HER2 Negative Breast Cancer	risovalisib Sensitive: C4 – Case Studies risovalisib Sensitive : C4	risovalisib Sensitive: C4 – Case Studies risovalisib Sensitive : C4
PIK3CA E542K	Gastric Cancer	PIK3CA E542K	Gastric Cancer	risovalisib Resistant: C4 – Case Studies risovalisib Resistant : C4	risovalisib Resistant: C4 – Case Studies risovalisib Resistant : C4