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DRUG:

Alecsat (cytotoxic lymphocyte-based cancer vaccine)

i
Other names: cytotoxic lymphocyte-based cancer vaccine
Associations
Company:
CytoVac
Drug class:
NK cell stimulant, Cytotoxic T lymphocyte stimulant
Related drugs:
Associations
8d
Adoptive cell transfer therapy with ex vivo primed peripheral lymphocytes in combination with chemotherapy in locally advanced or metastatic triple-negative breast cancer: the ImmunoBreast phase Ib clinical trial. (PubMed, J Immunother Cancer)
ALECSAT, in combination with carboplatin and gemcitabine, was safe, well tolerated, and demonstrated promising antitumor activity in mTNBC. These findings support further investigation in larger clinical trials.
P1 data • Preclinical • Journal
|
CD8 (cluster of differentiation 8)
|
carboplatin • gemcitabine • Alecsat (cytotoxic lymphocyte-based cancer vaccine)
5years
ImmunoBreast - A Phase Ib Study (clinicaltrials.gov)
P1/2, N=20, Recruiting, Henrik Ditzel
Clinical • New P1/2 trial
|
HER-2 (Human epidermal growth factor receptor 2) • ER (Estrogen receptor)
|
HER-2 positive • HR positive • ER expression
|
carboplatin • gemcitabine • Alecsat (cytotoxic lymphocyte-based cancer vaccine)