^
    16h
    Study to Evaluate the Therapeutic Equivalence and Safety of Fluticasone Furoate and Vilanterol Inhalation Powder 100 mcg/25 mcg and BREO ELLIPTA 100 mcg/25 mcg in Participants With Asthma (clinicaltrials.gov)
    P3, N=1430, Not yet recruiting, Sandoz | Initiation date: Jan 2026 --> Apr 2026
    Trial initiation date
    19h
    Perioperative Steroid Dosing on the APR in AIS (clinicaltrials.gov)
    P4, N=50, Recruiting, Emory University | Trial completion date: Dec 2025 --> Mar 2026 | Trial primary completion date: Dec 2025 --> Mar 2026
    Trial completion date • Trial primary completion date
    |
    dexamethasone
    2d
    Largely Distinct Post-Translational Modifications Differentiate Skeletal Muscle Wasting Caused by Cancer, Dexamethasone and Aging. (PubMed, J Cachexia Sarcopenia Muscle)
    These analyses identify atrophy-associated PTMs that provide refined biomarkers for fingerprinting the atrophic stimulus. Although most PTMs are stimulus-specific, P27 dihydroxylation of Lrpprc declines during muscle wasting induced by cancer, dexamethasone and aging, suggesting that this is a general atrophy marker. Experimental up-regulation of the atrophy-mimicking variant LrpprcP27A reduces muscle force compared to wild-type Lrpprc in young and old mice, suggesting that atrophy-associated P27 dihydroxylation contributes to disease-associated muscle weakness.
    Journal
    |
    COL6A2 (Collagen Type VI Alpha 2 Chain) • LRPPRC (Leucine Rich Pentatricopeptide Repeat Containing)
    |
    dexamethasone
    3d
    Hydrocortisone and Fludrocortisone for the Treatment of Septic Shock (clinicaltrials.gov)
    P4, N=336, Not yet recruiting, Northern Jiangsu People's Hospital
    New P4 trial
    4d
    Impact of Dexamethasone Route on Pain and Inflammation in iPACK With ACB for Knee Arthroplasty (clinicaltrials.gov)
    P4, N=90, Recruiting, Poznan University of Medical Sciences | Trial completion date: Oct 2025 --> Oct 2026 | Trial primary completion date: Sep 2025 --> Sep 2026
    Trial completion date • Trial primary completion date
    |
    dexamethasone injection
    4d
    Dexamethasone vs Dexmedetomidine in Sphenopalatine Ganglion Block for Rhinoplasty Pain (clinicaltrials.gov)
    P1, N=90, Enrolling by invitation, Ain Shams University
    New P1 trial
    |
    dexamethasone
    4d
    Increased immunogenicity of hypermutated SB28 syngeneic glioblastoma is partially mediated by alterations in tumor chemokine expression. (PubMed, Neurooncol Adv)
    Clones were injected subcutaneously or intracranially with or without anti-PD-1/anti-CTLA4 and dexamethasone...Rather, rejection depended on increased secretion of pro-inflammatory chemokines. Msh2 and Mlh1 loss was not equivalent, suggesting that additional studies are needed to elucidate germline and somatic mismatch repair gene-specific immune alterations.
    Journal • Tumor mutational burden • PD(L)-1 Biomarker • IO biomarker
    |
    TMB (Tumor Mutational Burden) • IFNG (Interferon, gamma) • MLH1 (MutL homolog 1) • MSH2 (MutS Homolog 2) • CXCL10 (Chemokine (C-X-C motif) ligand 10) • RAG1 (Recombination Activating 1)
    |
    TMB-H • MSI-H/dMMR • TMB-L
    |
    dexamethasone
    5d
    The Effect of Corticosteroids on Quality of Life Following Total Hip Arthroplasty: HIPSTER Study (clinicaltrials.gov)
    P4, N=224, Not yet recruiting, Ziekenhuis Oost-Limburg
    New P4 trial • HEOR
    |
    dexamethasone injection
    6d
    Autologous rectal mucosal esophageal transplantation for the prevention of strictures after ESD surgery for large-area early esophageal cancer: a multicenter clinical randomised controlled study (ChiCTR2500104316)
    P=N/A, N=60, Not yet recruiting, Department of Gastroenterology, Second Affiliated Hospital of Army Medical University; The Second Affiliated Hospital of the Army Medical University | N=36 --> 60 | Initiation date: Jun 2025 --> Oct 2025
    Enrollment change • Trial initiation date
    6d
    The influence of dexamethasone on postoperative pulmonary complications in elderly patients undergoing upper abdominal surgery (ChiCTR2600116998)
    P=N/A, N=546, Not yet recruiting, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; Union Hospital, Tongji Medical College, Huazhong University of
    New trial
    |
    dexamethasone
    6d
    Dexamethasone or Ondansetron Combined with Metaraminol for Preventing Postoperative Hypotension After Combined Spinal-Epidural Anesthesia in Cesarean Section: A Randomized, Double-Blind, Controlled Trial (ChiCTR2600117048)
    P=N/A, N=120, Not yet recruiting, The First Affiliated Hospital of Anhui Medical University; The First Affiliated Hospital of Anhui Medical University
    New trial
    |
    dexamethasone • ondansetron
    6d
    Comparison of postoperative analgesic effects of ultrasound-guided quadratus lumborum block at the arcuate ligament versus transversus abdominis plane block in cesarean section (ChiCTR2600116513)
    P=N/A, N=72, Not yet recruiting, The Second Affiliated Hospital of Shandong First Medical University; The Second Affiliated Hospital of Shandong First Medical University
    New trial
    |
    dexamethasone