^
2d
Enrollment closed
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PD-L1 (Programmed death ligand 1) • ALK (Anaplastic lymphoma kinase) • ROS1 (Proto-Oncogene Tyrosine-Protein Kinase ROS)
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ALK positive • ALK fusion • ROS1 fusion • ROS1 positive
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PD-L1 IHC 22C3 pharmDx • VENTANA PD-L1 (SP263) Assay
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Imfinzi (durvalumab) • Rozlytrek (entrectinib) • Alecensa (alectinib)
2d
Study Of Ruxolitinib (INCB018424) With Preoperative Chemotherapy For Triple Negative Inflammatory Breast Cancer (clinicaltrials.gov)
P2, N=23, Active, not recruiting, Dana-Farber Cancer Institute | Trial completion date: Dec 2025 --> Apr 2026
Trial completion date
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HER-2 (Human epidermal growth factor receptor 2) • PGR (Progesterone receptor)
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HER-2 negative
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paclitaxel • doxorubicin hydrochloride • Jakafi (ruxolitinib) • cyclophosphamide
2d
MDS: Pacritinib With Aza for Upfront Myelodysplastic Syndrome (clinicaltrials.gov)
P1/2, N=25, Not yet recruiting, Thomas Jefferson University
New P1/2 trial
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azacitidine • Vonjo (pacritinib)
6d
A Study to Evaluate the Safety and Efficacy of Baricitinib in the Treatment of Frontal Fibrosing Alopecia (FFA) (clinicaltrials.gov)
P4, N=15, Active, not recruiting, University of Alabama at Birmingham | Recruiting --> Active, not recruiting
Enrollment closed
6d
NCI-2020-01626: Peritransplant Ruxolitinib for Patients With Primary and Secondary Myelofibrosis (clinicaltrials.gov)
P2, N=79, Active, not recruiting, Fred Hutchinson Cancer Center | Recruiting --> Active, not recruiting | N=60 --> 79 | Trial completion date: Dec 2029 --> Apr 2030
Enrollment closed • Enrollment change • Trial completion date
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Jakafi (ruxolitinib) • cyclophosphamide • methotrexate • melphalan • fludarabine IV • busulfan
7d
A clinical study of ruxolitinib combined with reduced-dose HLH-1994 regimen in the treatment of adult hemophagocytic lymphohistiocytosis (ChiCTR2500115370)
P=N/A, N=20, Not yet recruiting, Shandong Provincial Qianfoshan Hospital; Shandong Provincial Qianfoshan Hospital
New trial
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Jakafi (ruxolitinib)
7d
A real-world study on the influencing factors of the efficacy of ruxolitinib cream in the treatment of vitiligo (ChiCTR2500115141)
P=N/A, N=170, Not yet recruiting, Peking University Third Hospital; Peking University Third Hospital
New trial
7d
New trial
7d
A Clinical Study on the Efficacy and Safety of JAK/ACVR1 Inhibitors in the Treatment of Steroid-resistant Chronic Graft-versus-Host Disease (ChiCTR2500112276)
P=N/A, N=40, Not yet recruiting, The Second Affiliated Hospital of the Army Medical University; The Second Affiliated Hospital of the Army Medical University
New trial
7d
Real-world study of The efficacy and safety of The JAK inhibitor Baricitinib and Ritlecitinib for the treatment of severe alopecia areata (ChiCTR2500114501)
P=N/A, N=150, Completed, The FIrst Affiliated Hospital, College of Medicine, Zhejiang University; The FIrst Affiliated Hospital, College of Medicine, Zhejiang University
New trial
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Litfulo (ritlecitinib)
7d
A Clinical Study on the Safety and Efficacy of Gecacitinib Hydrochloride Tablets in the Treatment of Myelodysplastic Syndromes (MDS) and Myelodysplastic Syndromes/Myeloproliferative Neoplasm (MDS/MPN)Patients with Anemia. (ChiCTR2500113178)
P4, N=48, Not yet recruiting, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College.; Institute of Hematolog
New P4 trial