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    DRUG:

    zorpocabtagene autoleucel (MB-CART 19.1)

    i
    Other names: MB-CART 19.1, MB-CART19.1, Miltenyi CD-19 CAR-T cell therapy, zorpo-cel
    Associations

    News

    Trials
    Company:
    Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Miltenyi Biomedicine
    Drug class:
    CD19-targeted CAR-T immunotherapy
    Related drugs:
    Associations

    News

    Trials
    10d
    MB-CART19.1 in Relapsed/Refractory Acute Lymphoblastic Leukemia (clinicaltrials.gov)
    P=N/A, N=12, Not yet recruiting, King Hussein Cancer Center
    New trial
    |
    CD19 (CD19 Molecule)
    |
    zorpocabtagene autoleucel (MB-CART 19.1)
    2ms
    Study of CART Cell (MB-CART19.1) in Patients With Relapsed or Refractory CD19 Positive NHL (clinicaltrials.gov)
    P2, N=26, Recruiting, King Hussein Cancer Center
    New P2 trial
    |
    zorpocabtagene autoleucel (MB-CART 19.1)
    2ms
    MB-CART19.1 r/r CD19+ B-cell Malignancies (BCM) (clinicaltrials.gov)
    P1, N=48, Active, not recruiting, Miltenyi Biomedicine GmbH | Phase classification: P1/2 --> P1
    Phase classification
    |
    CD19 (CD19 Molecule)
    |
    zorpocabtagene autoleucel (MB-CART 19.1)
    4ms
    MB-CART19.1 in Refractory SLE (clinicaltrials.gov)
    P1/2, N=29, Recruiting, Miltenyi Biomedicine GmbH | Trial primary completion date: Aug 2025 --> Sep 2027
    Trial primary completion date
    |
    zorpocabtagene autoleucel (MB-CART 19.1)
    6ms
    A Study of MB-CART19.1 Cellular Therapy for People With Central Nervous System Lymphoma (CNSL) (clinicaltrials.gov)
    P1, N=12, Recruiting, Memorial Sloan Kettering Cancer Center
    New P1 trial
    |
    zorpocabtagene autoleucel (MB-CART 19.1)
    6ms
    MB-CART19.1 r/r CD19+ B-cell Malignancies (BCM) (clinicaltrials.gov)
    P1/2, N=48, Active, not recruiting, Miltenyi Biomedicine GmbH | Recruiting --> Active, not recruiting
    Enrollment closed
    |
    CD19 (CD19 Molecule)
    |
    zorpocabtagene autoleucel (MB-CART 19.1)
    9ms
    MB-CART19.1 r/r CD19+ B-cell Malignancies (BCM) (clinicaltrials.gov)
    P1/2, N=48, Recruiting, Miltenyi Biomedicine GmbH | Trial completion date: Dec 2024 --> Mar 2026 | Trial primary completion date: Dec 2024 --> Mar 2026
    Trial completion date • Trial primary completion date
    |
    CD19 (CD19 Molecule)
    |
    zorpocabtagene autoleucel (MB-CART 19.1)
    over1year
    MB-CART19.1 in Refractory SLE (clinicaltrials.gov)
    P1/2, N=29, Recruiting, Miltenyi Biomedicine GmbH | Not yet recruiting --> Recruiting | Trial completion date: Mar 2027 --> Aug 2027 | Initiation date: Mar 2024 --> Aug 2024 | Trial primary completion date: Mar 2025 --> Aug 2025
    Enrollment open • Trial completion date • Trial initiation date • Trial primary completion date
    |
    zorpocabtagene autoleucel (MB-CART 19.1)
    over1year
    CAR T cell therapy for CD19-positive cancer - phase I clinical trial (ACTRN12621000762853)
    P1, N=25, Recruiting, Metro North Hospital and Health Service | N=15 --> 25
    Enrollment change • CAR T-Cell Therapy
    |
    CD19 (CD19 Molecule)
    |
    cyclophosphamide • zorpocabtagene autoleucel (MB-CART 19.1)
    over1year
    LONGSAFE: Long-Term Follow-up of Patients Treated With Miltenyi Cell and Gene Therapies (clinicaltrials.gov)
    P=N/A, N=40, Recruiting, Miltenyi Biomedicine GmbH
    New trial • Gene therapy
    |
    MB-CART20.1 • zamtocabtagene autoleucel (MB-CART2019.1) • zorpocabtagene autoleucel (MB-CART 19.1)
    over1year
    MB-CART19.1 r/r CD19+ B-cell Malignancies (BCM) (clinicaltrials.gov)
    P1/2, N=48, Recruiting, Miltenyi Biomedicine GmbH | Trial primary completion date: Dec 2023 --> Dec 2024
    Trial primary completion date
    |
    CD19 (CD19 Molecule)
    |
    zorpocabtagene autoleucel (MB-CART 19.1)
    2years
    MB-CART19.1 r/r CD19+ B-cell Malignancies (BCM) (clinicaltrials.gov)
    P1/2, N=48, Recruiting, Miltenyi Biomedicine GmbH
    Trial completion date • Trial primary completion date
    |
    CD19 (CD19 Molecule)
    |
    CD19 expression
    |
    zorpocabtagene autoleucel (MB-CART 19.1)